Orotic Acid (CAS 65-86-1): High Purity 99% White Crystalline Powder-ZHC Chemical Co.,Ltd.

Specification:

Item	Specifications
Assay	≥99.0%
Residue on ignition	≤0.20%
Heavy metal (Pb)	≤20ppm
Loss on drying	≤1.0%
PH	2.2~3.0
form	Crystalline Powder
color	White
Water Solubility	Slightly soluble
Stability:	Stable. Incompatible with strong oxidizing agents.
Appearance	White powder
structural

Orotic Acid: An Overview

Orotic acid is a naturally occurring compound produced by the gut microbiota in the human body. Also known as vitamin B13 or pyrimidine carboxylic acid, it is not a true vitamin—a classification it acquired in the 1960s when researchers incorporated it into laboratory animal diets for nutritional studies. When added to dietary regimens, supports cardiovascular health and delivers benefits comparable to those of essential vitamins.

Application Fields

Orotic acid, also known as Vitamin B13, is a type of nutrient. In the pharmaceutical field, orotic acid and its derivatives have shown good therapeutic effects on icteric hepatitis, fatty liver, and acute and chronic hepatitis (Chemicalbook). As a nutrient-based cosmetic matrix, it can be well absorbed by the skin, promote cell metabolism, and significantly inhibit skin aging. Additionally, orotic acid finds applications in the food industry and life sciences field.

Chemical Synthesis Method

To synthesize orotic acid, follow these steps: First, condense diethyl oxalate with acetic acid and cyclize the product with urea to yield 5-ethoxycarbonylmethylene hydantoin. Then, perform ring expansion on this intermediate and finish with acid precipitation to obtain the final product.

Storage

CAS 65-86-1 should be stored in a cool and dry place.

Chemical Properties

CAS 65-86-1 appears as a white crystalline powder. It is very slightly soluble in alcohols and organic solvents, and insoluble in ethers. It forms salts and dissolves when in contact with alkalis. Its maximum absorption wavelength is 282 nm.

Package and Shipping:

25kg/drum , or 20kg/carton

Storage:

Keep dry and cool place.